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• Business: Biotechnology and Pharmaceuticals: Pharmaceuticals: Research and Development  (170)

• Archemix Corp. - Company developing therapeutics of aptamers, for the prevention and treatment of chronic and acute disease. Includes overview of technology and commercial potential, careers and contacts in Cambridge, Massachusetts.
• Arena Pharmaceuticals, Inc. - Receptor-based drug discovery in the fields of diabetes, obesity, cardiovascular, sleep disorders, neurodegeneration, schizophrenia, depression and anxiety. Comprehensive profile of company in San Diego, California. (Nasdaq: ARNA)
• AVI Biopharma, Inc. - Develops and commercializes a vaccine against human chorionic gonadotropin secreting cancers, and synthetic antisense technology to inhibit translation in treating cardiovascular, kidney and viral diseases. Research and manufacturing facilities in Corvallis, Oregon. (Nasdaq: AVII)
• Avigen, Inc. - Develops gene-based therapeutic products derived from adeno-associated virus for the treatment of inherited and acquired diseases. Includes explanation of technology, product pipeline, collaborative partnerships and investment data, from manufacturing facility in Alameda, California. (Nasdaq: AVGN)
• BioSphings AG. - Development and marketing of products to treat viral infections, cancer and autoimmune diseases. Features product pipeline and company details. Frankfurt, Germany.
• Can Fite BioPharma Ltd. - Developer of anti-arthritis drug CF101 presents its management, technology, and research pipeline. Includes a list of publications and patents.
• Curis, Inc - Developing small molecule and peptide drugs in regulatory signaling and regenerative pathways. Introduces technical background, product pipeline, collaborations, investment data and careers headquartered from Cambridge, Massachusetts. (Nasdaq: CVGP)
• Cyano Biotech GmbH. - Identifies and characterises structural variants of polyketides and non-ribosomal cyclic heptapeptides from cyanobacteria, and optimises pharmacological activity using biocombinatorial techniques. Profile, collaborators and contacts in Germany.
• EntreMed, Inc. - Researches and develops biopharmaceutical products which address the role of blood and blood vessels in the prevention and treatment of diseases by inhibiting growth or enhancing bioavailability of drugs. Based in Rockville, Maryland. (Nasdaq: ENMD)
• Gemac - Researching diagnostics and drug candidates for the treatment of amyotrophic lateral and multiple sclerosis, as well as autoimmune diseases, including anti-idiotypic antibodies. Includes overview of corporation in Cenon, France.
• Genelabs Technologies, Inc. - Discovers, develops and commercializes therapies for systemic lupus erythematosus, viral diseases and cancer. Located in Redwood City, California.(Nasdaq: GNLB)
• Genentech, Inc. - Genetic engineering techniques in the discovery, development, production, and marketing of human therapeutics. Includes research history, product pipline, global corporate and career information, from South San Francisco, California.
• Genfit - Researching nuclear receptors and gene deregulation for treatment of cardiovascular, metabolic and inflammatory diseases. Includes information about genomic research headquartered in Loos, France.
• Hemobiotech Inc. - Developer of blood substitute, aiming to address intrinsic hemoglobin toxicity. Introduction to company and their work, with form to contact Dallas, Texas.
• Imclone Systems Inc. - Researches and develops growth factor blockers and anti-cancer vaccines. Includes clinical programs, investor details and overview of company in New York City. (Nasdaq: IMCL)
• Intrabiotics Pharmaceuticals, Inc. - Develops antibacterial and antifungal drugs, including protegrins and related antimicrobial peptides, for application in cystic fibrosis. Includes pipeline, publications, and investor information from Palo Alto, California. (Nasdaq: IBPI)
• Intra-Cellular Therapies, Inc. - Developing novel drugs against targets inside nerve cells to treat CNS disorders. Includes therapeutic projects, target biochemistry, corporate data and contacts for headquarters in New York City.
• Isologen, Inc - Development and marketing of an autologous cellular system for use in cosmetic medicine and dentistry, with company profile and details of the culture process. Headquarters in Pennsylvania, USA.
• MannKind Corp. - Developing a pulmonary insulin delivery system, and immunotherapy of cancer, by identifying tumor-related antigens, DNA and peptide-based drugs evoking cell-mediated responses. Located in Valencia, California.
• Maxygen, Inc. - Develops proprietary protein modifications including PEG, glycosylation and vaccines. Overview of technologies, clinical trial pipeline, investor data and careers in Redwood City, California. (Nasdaq: MAXY)
• Mixture Sciences, Inc. - A privately held company that specializes in research for treatment of cancer, diabetes, multiple sclerosis, HIV/AIDS and infectious diseases, including Lyme Disease. Lists research projects and procedures. Based in San Diego, California.
• m-phasys GmbH - Focused on the discovery of therapeutics for GPCRs and other membrane proteins. Information on research activities, services, management, press releases and directions. Located in Tübingen, Germany.
• Nephros Therapeutics, Inc. - Specialist in the design, development, and marketing of human cell replacement therapy systems, targeting inflammatory disease. Includes directions to research labs at Ann Arbor, Michigan, and corporate offices in Lincoln, Rhode Island.
• Neurobiological Technologies, Inc. - Emerging drug development company focused on the clinical development and regulatory approval of neuroscience drugs. Includes news and product and investor information.
• Neurocrine Biosciences, Inc. - Discovers and develops therapeutics for treatment of diseases and disorders of the central nervous and immune systems, including anxiety, depression, alzheimer's disease, obesity, stroke and multiple sclerosis. (Nasdaq: NBIX).
• Neurogen Corporation - Discovers, develops, manufactures and markets products for the treatment of psychiatric and neurological disorders such as obesity and other eating disorders, anxiety, schizophrenia, sleep disorders, cognitive impairment, depression, epilepsy and stress disorders. (Nasdaq: NRGN).
• Novacta Biosystems Ltd. - Drug discovery and development company using pathway engineering and chemistry to optimise the activity of natural products for the treatment of infectious diseases. Introduces biotransformation technology, lead compounds, key personnel in Hatfield, England.
• Nymox Pharmaceutical Corp. - Researches and develops neurological diagnostics and pharmaceuticals for the aging population with emphasis on Alzheimer's disease. Profile of company with bases in Maywood, New Jersey and Saint Laurent, Quebec. (Nasdaq: NYMX)
• Optimer Pharmaceuticals - Develops late-stage anti-infective and preclinical antibiotics by carbohydrate technology.
• Rib-X Pharmaceuticals Inc. - Structure-based drug design start-up, specializing in the ribosome as a target, and bacterial antibiotic resistance. Includes mechanisms of action, glossary, careers, corporate news and contacts and directions in New Haven, Connecticut.
• Sequenom, Inc. - Researches and develops high definition dna analysis tools for industrial biomedical and life science applications. (Nasdaq: SQNM).
• Sierra Sciences Inc. - Developing drugs and therapies to reverse the effects of human aging by focusing on preserving the length of telomeres, to keep them more resilient. Careers in Reno, Nevada.
• Synaptic Pharmaceutical Corp. - Applies human receptor-targeted drug design technology to discover and clone genes and to design G protein-coupled receptor agonist and antagonists. Based in Paramus, New Jersey. (Nasdaq: SNAP)
• Trophogen, Inc - Development of superactive hormones and growth factors for therapeutic applications. Based in Rockville, Maryland, USA.
• Voyager Pharmaceutical Corp. - Specializes in age-related diseases. Includes patient links for Alzheimer's Disease, clinical trials, company news and careers in Raleigh, North Carolina.
• Xencor, Inc. - Technology for MHC epitope removal, glycosylation to optimize pharmacokinetics, masking immune recognition sites and engineering monoclonal antibodies. Includes discovery programs, partnering opportunities in Monrovia, California. ImmunoPDAâ„¢ Technology Product Sheet Caltech spin-off developing proteomic technologies to accelerate drug discovery.
• Xoma - Development and manufacture of recombinant proteins and peptides, in partnership with big pharmas. Includes licensing of technology derived from the host-defense protein BPI, monoclonal antibodies to treat chemotherapy-induced thrombocytopenia, and to target cancer. Based in Berkeley, California.
• ZymoGenetics, Inc. - Discovery, development and commercialization of therapeutic proteins for the prevention and treatment of human diseases. Includes product pipeline, news on clinical trials and profile of company in Seattle, Washington.

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